QB – Patrick Mahomes
After coming back in week 10 and looking like the Patrick Mahomes that kicked the NFL’s collective ass for the last 3 seasons, you can count on Mahomes dialing up some more Tyreek Hill action this week against Dallas.
RB – Alvin Kamara and Joe Mixon
Kamara missed last week’s game against Tennessee, so be careful with this one and closely watch his status heading into Sunday’s matchup with the Eagles. Joe Mixon is ready to take advantage of the Raiders, whose defense allowed a monster game to the aforementioned Mahomes and Darrel Williams last week.
WR – Russell Gage, Jakobi Meyers and Cedric Wilson
This is the part of the lineup where you just need cheap production. None of these guys are going to win you the week, but if you can get an average performance out of 2 of the 3, you will have major flexibility throughout the rest of your lineup.
TE – Mo Alie-Cox
Again, cheap production here as well. Alie-Cox is going to get targets as Carson Wentz tries to get the Colts above .500 on the season, likely while running for his life against this solid Buffalo defense.
FLEX – Jonathan Taylor
This right here is why you went cheap at TE and RB in this lineup. Taylor is tied with Derrick Henry for the most rushing yards in the league through week 10. The Colts have recently made a huge re-commitment to the running game as their season was slipping away from them, which bodes well for Taylor’s workload.
DEFENSE – Cleveland Browns
They’re playing the Lions (enough said), and with Dan Campbell having recently taken over play calling duties for Detroit, this could get very ugly very quickly.